Neurobiology of the Bronchopulmonary System
Overview
Organization: National Heart, Lung, and Blood Institute
Start Date: 03/2021
End Date: 02/2028
Primary Goal: Goal 4: Increase and sustain research to better understand the prevention, pathogenesis, diagnosis, treatment, and management of COPD.
Secondary Goal(s):
Objective(s):
- Help expand, coordinate, and optimize COPD research efforts
- Improve methods for earliest detection and diagnosis and develop effective strategies for preventing the onset and progression of COPD
- Define and characterize the pathogenesis of COPD heterogeneity
- Promote research that can lead to strategies that help prevent the onset and progression of COPD and improve the quality of COPD care and management
Collaboration: Johns Hopkins University
Activity Type: Research
Activity Description
This NHLBI-funded research activity is being carried out by Johns Hopkins University.Basic and clinical research over the past decade is shedding new light on the major role played by the nervous system in asthma, COPD, and chronic coughing. This study focuses on unraveling the chemical and ionic mechanisms of airway nerve activation and on identifying the specific aspects of airway inflammation, especially during early life that leads to a hyperactive neuronal state in the airways. The findings will increase our understanding of airway biology, and will continue to define new therapeutic targets aimed at reducing the suffering of those with inflammatory airway diseases.
Audience
General Audience: Researchers
Focused Audience: n/a
Program Reach: National
Type of Area: N/A
Setting: Workplace
Cost and Funding Sources
This activity was funded through the National Heart, Lung, and Blood Institute.Impact Analysis
Results of program are in progressAdvice or Lessons Learned
In processContact Information
National Heart, Lung, and Blood Institute
Program Analyst
Bethesda
Maryland