COPD National Action Plan:
Community Action Tool
Discover the progress the COPD community has made toward implementing the goals and objectives in the COPD National Action Plan.

COPD Cachexia: Deciphering the Impact of Antioxidants, Iron and Mitochondrial Function Using 'Omics Approaches

Overview

Organization: National Heart, Lung, and Blood Institute
Start Date: 06/2021
End Date: 06/2025
Primary Goal: Goal 4: Increase and sustain research to better understand the prevention, pathogenesis, diagnosis, treatment, and management of COPD.
Secondary Goal(s):
Objective(s):
  • Help expand, coordinate, and optimize COPD research efforts
  • Improve methods for earliest detection and diagnosis and develop effective strategies for preventing the onset and progression of COPD
  • Define and characterize the pathogenesis of COPD heterogeneity
  • Promote research that can lead to strategies that help prevent the onset and progression of COPD and improve the quality of COPD care and management
Collaboration: University of Alabama at Birmingham
Activity Type: Research

Activity Description

This NHLBI-funded research activity is being carried out by University of Alabama at Birmingham.

Chronic Obstructive Pulmonary Disease (COPD) is the fourth leading cause of death in the United States with mortality continuing to rise despite advances in medicine. Cachexia, a form of muscle wasting, is a debilitating co-morbidity whose prevalence increases with severity of COPD. Elucidating mechanisms of mitochondrial dysfunction in COPD cachexia has the potential to aid the development of therapeutics targeting mitochondrial oxidative stress.

Audience

General Audience: Health professionals, Researchers
Focused Audience: n/a
Program Reach: National
Type of Area: N/A
Setting: Workplace

Cost and Funding Sources

This activity was funded through the National Heart, Lung, and Blood Institute.

Impact Analysis

In process

Advice or Lessons Learned

In process

Contact Information

Sarah Olscamp
National Heart, Lung, and Blood Institute
Program Analyst
Bethesda
Maryland