Integrative Genomic, Transcriptomic and Proteomic Studies of Pulmonary Function and COPD
Overview
Organization: National Heart, Lung, and Blood Institute
Start Date: 08/2021
End Date: 07/2025
Primary Goal: Goal 4: Increase and sustain research to better understand the prevention, pathogenesis, diagnosis, treatment, and management of COPD.
Secondary Goal(s):
Objective(s):
- Help expand, coordinate, and optimize COPD research efforts
- Improve methods for earliest detection and diagnosis and develop effective strategies for preventing the onset and progression of COPD
- Define and characterize the pathogenesis of COPD heterogeneity
- Promote research that can lead to strategies that help prevent the onset and progression of COPD and improve the quality of COPD care and management
Collaboration: University of Virginia
Activity Type: Research
Activity Description
This NHLBI-funded research activity is being carried out by University of Virginia.Chronic obstructive pulmonary disease (COPD) is a leading cause of death in the United States and worldwide. In this study, we combine whole genome sequence analysis of COPD and related pulmonary function traits with comprehensive gene expression and proteomic measures from multi-ethnic cohorts including African American, Hispanic and European ancestry participants. Our study will leverage these multiple sources of data to identify genes, biomarkers and biological mechanisms contributing to risk of COPD.
Audience
General Audience: Health professionals, Researchers
Focused Audience: n/a
Program Reach: National
Type of Area: N/A
Setting: Workplace
Cost and Funding Sources
This activity was funded through the National Heart, Lung, and Blood Institute.Impact Analysis
Results of program are in progressAdvice or Lessons Learned
In processContact Information
National Heart, Lung, and Blood Institute
Program Analyst
Bethesda
Maryland